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Research And Product Studies |


 



 
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Hair Loss Hair Growth Information |
 



 



 
 



 



 



 
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This landmark Patient Study with Hair Genesis is also
published on PubMed.gov, a service of the National Library of
Medicine and the National Institutes of Health (NIH) -- one of
the most respected and authoritative sources of published
medical information online. |
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Original Landmark
HairGenesis Published IRB-Study
( First Successfully Tested Botanical Hairloss Product ) |

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Recent University-Based, Science Research Study
( First Dual Mechanism of Action Hairloss Product ) |
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Chronic inflammation of
the hair follicle is considered a contributing factor in the patho-genesis of
AndroGenetic Alopecia (AGA). Previously, we
clinically tested LipoSterolic Extract of Serenoa repens (LSESr -
Saw Palmetto)
and its glycoside, Beta-Sitosterol, in subjects with AGA and
showed a highly positive response to treatment. In the most recent
University-based science study, we
sought to determine whether blocking of inflammation using a
composition containing LSESr as well as two Anti-Inflammatory
agents (carnitine and thioctic acid) could alter the expression of
molecular markers of inflammation in a well-established in vitro
system.
Using a well-validated assay representative of
hair follicle keratinocytes, specifically, stimulation of cultured human
keratinocyte cells in vitro, we measured changes in gene
expression of a spectrum of well-known inflammatory markers.
Lipopolysaccharide (LPS) provided an inflammatory stimulus. In
particular, we found that the composition effectively suppressed
LPS-activated gene expression of chemokines, including CCL17,
CXCL6 and LTB(4) associated with pathways involved in inflammation
and apoptosis. Our data supports the hypothesis that the test
compound exhibits Anti-Inflammatory characteristics in a
well-established in vitro assay representing hair follicle keratinocyte gene
expression. These findings suggest that 5-Alpha Reductase
inhibitors (DHT Blockers) combined with blocking of inflammatory processes could
represent a unique two-pronged approach (Dual Mechanism of Action)
in the treatment of pattern hair loss with improved effectiveness over
all other current hair loss treatment products. READ
the FULL ARTICLE
Evidence
Based Complementary Alternative Medicine |
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Who
Can Benefit From Using The HairGenesis™ Hair Loss Treatment ?

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